Hypertrophic Osteodystrophy Bone Disease on Dogs

HOD Bone Disease on Dogs

Hypertrophic Osteodystrophy or HOD is a condition that affects young large breed dogs. HOD is a bone disease that affects the rapid growing bones of giant dog breeds and may occur between ages of 2 and 7 months. The breeds that are at high risk for HOD are Boxers, Chesapeake Shepherd Dog, Golden Retriever, Great Dane, Irish Setter, Labrador Retriever and Weimaraner, although there can be exceptions to this rule. Commonly, large male dog breeds are more affected than females. Inherited or genetic link seen to be affects in occurrence of this disease. They need proper petsafe and care

There is currently unknown or no agreement on the cause of Hypertrophic osteodystrophy. Possible causes maybe considered are; bacterial infections, canine distemper virus infection, vaccination with distemper virus or any other viral infections. Also Vitamin C deficiency is also speculated, hence the decreased uptake of Vitamin C and/or increased uptake of other vitamins and minerals other than vitamin C. The excessive calcium supplementation is also included as one possibility. There may be a link to recent vaccination with a modified live vaccine, but no specific vaccine has been implicated. on Weinmaraner dog breeds, it is recommended for them to receive killed virus vaccines instead of modified live or separate vaccines for canine distemper, parvovirus, and adenovirus to prevent the possibility of vaccine-induced HOD.

The signs and symptoms of HOD strick in often to be mild to moderate painful swelling of the growth plates in the leg bones of dogs. It most commonly affects the ends of the radius, ulna (the long bones from the elbow to the wrist) and tibia (the long bone from the knee to the hock). Lameness may vary from mild to sever, reluctance to stand if multiple limbs are affected. Fever, anorexia, loss of appetite and depressions are noticed. Swelling and heat are commonly present over the affected bones. Some clinical signs also includes diarrhea, discharge from the eyes, tonsillitis, thickening of the foot pads, pneumonia, and abnormal development of the enamel of the teeth.

X-ray signs of HOD are more clearly noticed. A line of lucency where the bone has been destroyed is usually found to be parallel to the growth plates of the affected bones. X-rays show a dark line at the metaphysis, which can progress to new bone growth on the outside of that area. This represents microfractures in the metaphysis and bone proliferation to bridge the defect in the periosteum. Some signs seen on microscope are also clear. The growth plate is normal, but blood vessels adjacent to the growth plate are frequently dilated. Bleeding in the bone adjacent to the growth plate and extensive death of the bone adjacent to the growth plate. Adjacent to the line of lucency is a zone of increased density of bone that corresponds to collapsed of layers of dead bone. The outer layer of the bone (periosteum) is thickened with new bone formation.

The treatment for HOD is generally supportive since this is a very painful condition and these disease is usually self-limiting which can last a few weeks, resting on dog crates. Treatment includes intravenous fluid therapy, anti-inflammatory and painkillers such as buffered aspirin or carprofen (Rimadyl) are given. In addition, the animals are usually given a broad-spectrum antibiotic since bacterial infection is suspected. Since the dog might be too irritable and uncomfortable, strict rest on a comfortable warm pet bed is recommended. Feeding a nutritious, highly palatable food will help to encourage some dogs to eat. In severe cases steroids may need to be given to control the pain, but because of the possibility of this being a bacterial disease their use may be contraindicated due to their immuno suppressive qualities. Supplementation of Vitamin C is contraindicated due to an increase in calcium levels in the blood, possibly worsening the disease. Permanent skeletal deformity can occur, recurrence can be a problem until the dog reaches maturity and dogs usually do not die of the disease rather are euthanize if recovery is poor or if clinical signs are severe.

Osteochondritis Dissecans: Dog Bones Disorder

In any joint in the body, two bones come together and movement is allowed between them, there is an exceptionally smooth area of cartilage covers in surface of each bone which acts as a cushion and protects the underlying bone. If anything disrupts this smooth cartilage surface, movement of the joint becomes painful, this is called Osteochondritis Dissecans. OCD usually affects shoulder, ankle, elbow and knee joints, and primarily seen in human, horse and dog. In dogs, OCD mainly strikes large dog breeds, and is fairly common in Golden Retrievers, German Shepherds, Rottweilers, Great Danes, Bernese Mountain Dogs, and Saint Bernards. Not all big breeds are vulnerable: OCD is less likely to affect Doberman Pinschers, Collies, and Siberian Huskies.

This disorder seems to be spontaneous and not so easy to predict. OCD often cause of rapid bone developments and usually found in puppies between ages four to eight months of age. OCD also ocassionally found in older dogs and small dog breeds, and the male dogs are more often affected almost five times than female dogs. OCD can be heriditary from any or both parents who had the condition. Other common cause of OCD are; too much stress on dogs young bones also, restricted blood flow to the cartilage, overweight problems, trauma, developed cracks on growing bones and weight bearing bones, or poor diet and nutrition. Proper petsafe is needed to ensure good health and wellness of dogs.

Every time this dog would move the joint or bear weight on it, the flap would irritate the underlying tissue and create pain and discomfort. That's why a dog limps with this condition. Injury to the surface cartilage may lead to the separation of the cartilage from the bone or cause a decrease in blood supply that leads to cartilage flap formation. Common signs of OCD are; limping dog leg, favoring one paw or leg while walking or even when lying down, swelling at the shoulder or, more rarely, the elbows and knees, pain and discomfort when trying to extend a swollen joint.

Osteochondritis Dissecans can be treated, one treatment method called "conservative treatment" requires the dog to be confined to pens or dog crates for number of weeks where activity and jumping will be kept to a minimum. After four to ten weeks of confinement there is about a sixty percent chance that the cartilage defect on the humeral head will heal and the dog will return to normal activity. The most direct approach and the one that returns the pup to normal activity the soonest is the surgical approach. In surgery the veterinarian makes an incision over the shoulder and accesses the shoulder joint. Opening the joint space the surgeon inspects for any loose cartilage pieces and rotates the humerus to expose the back side of the head of the humerus where the defect comes into view. For growing puppies, it has been recommended that animals that are susceptible to the disease be fed a diet that is lower in protein and fat, or that they are fed in a limited manner to allow steady even growth during the first year of life. This theory may have merits, but more specific studies need to be done before any general recommendations can be made. Some people believe that an overweight growing dog will be more likely to develop OCD, but there isn't much evidence yet. Protect a young pup's limbs from unnecessary physical impact, such as repeated jumps off a deck or out of a car. Proper diet certainly play a role, choose healthy, natural and balanced puppy diet that promote healthy bone growth and may reduce your dog's odds of getting OCD.